Route 78 Street Bar

Depew | American | Lunch | Dinner

Location & Contact

6036 Transit Road
Depew, NY 14043

Phone: 716-685-5665

View Menu

Kitchen Hours

  • Monday: 4:00PM - 10:00PM
  • Tuesday: 4:00PM - 10:00PM
  • Wednesday: 4:00PM - 10:00PM
  • Thursday: 4:00PM - 10:00PM
  • Friday: 12:00PM - 10:00PM
  • Saturday: 12:00PM - 10:00PM
  • Sunday: 12:00PM - 9:00PM


Welcome to Route 78 Street Bar!

We are located at 6036 Transit road in Depew, just minutes from the Buffalo/ Niagara airport. At Route 78 Street Bar we make everything handmade. We use local produce, products and beverages. All ingredients are brought in fresh daily. The team at Route 78 Street Bar’s goal is to pamper you with excellent service and provide the public with great restaurant and bar experience at reasonable prices. We have 20 craft beers on tap, spirits, and 14 wines from around the world. Enjoy responsibly while watching the Buffalo Bills and Sabres on one of our 15 big screen TV’s! We have something for everyone!